Context:T-cell Lymphoma is a common hematological malignancy in Kosovo compared to the other lymphoid malignancies. These are a variety of subtypes of the disease present. The diagnosis of this disease has increased in the last years and the treatment with chemotherapy and other supportive care has many challenges.
Design: Cross sectional retrospective epidemiological study. The data was collected during the period of June 2018 to June 2023.
Setting: The data was collected from the chemotherapy treatment protocol books in the Hematology clinic of the UCC Kosovo.
Patients and other participants: Adults, age 18 and older, both genders, diagnosed, treated with T-cell Lymphoma in the Hematology clinic of Kosovo. The diagnosis was made based on histo-pathological and immunohistochemical analysis of lymph nodes or bone marrow biopsies
Interventions: none.
Results: During the period specified above, 44 patients were diagnosed and treated with T-cell lymphoma, the most common was Anaplastic large T-cell lymphoma with 9(19.5%) then Enteropathy associated T-cell lymphoma with 7(14.6%), NK/T-cell lymphoma with 5 (9.7%). One rare example of T Lymphoma/ Leukemia accompanied by cirrhosis hepatis and another with T-cell lymphoma was a patient diagnosed with gamma/delta T-cell lymphoma, which was the only such case in our clinic. From the patients diagnosed with T-cell Lymphoma during this period, 29 were treated with the CHOP protocol as first line chemotherapy.
Conclusions: The majority of patients were treated with CHOP chemotherapy protocol as first line therapy. The results of the treatments were successful in achieving remissions in a small number of patients. The patients that did not achieve remission received a second treatment protocol with mixed results and were sent to transplant center.
